产品
编 号：F167518
分子式：C15H21Br2IN4S
分子量：576.13
分子式：C15H21Br2IN4S
分子量：576.13
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 145196-87-8
产品详情
生物活性：
Iodophenpropit dihydrobromide is a potent and selective histamine H3 receptor antagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD 0.32 nM).
体内研究：
Iodophenpropit (1 μg/kg; through intramuscular; b.i.d.; for 10 days) shows significant enhancement of total anti- sheep red blood cells (SRBC)- immunoglobulins (Igs) in rabbits.Animal Model:New Zealand adult healthy rabbits of either sex weighing 1.63±0.36 kg
Dosage:1 μg/kg
Administration:Administered through intramuscular (i.m.); b.i.d.; for 10 days
Result:Could influence a detectable antibody response to SRBC.
体外研究：
Iodophenpropit is a very potent H3 receptor antagonist and shows only a moderate affinity for the H1 and H2 receptor.Iodophenpropit inhibit 5-hydroxytryptamine (5-HT) responses with an IC50 of 1.57±0.3 μM.
Iodophenpropit dihydrobromide is a potent and selective histamine H3 receptor antagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD 0.32 nM).
体内研究：
Iodophenpropit (1 μg/kg; through intramuscular; b.i.d.; for 10 days) shows significant enhancement of total anti- sheep red blood cells (SRBC)- immunoglobulins (Igs) in rabbits.Animal Model:New Zealand adult healthy rabbits of either sex weighing 1.63±0.36 kg
Dosage:1 μg/kg
Administration:Administered through intramuscular (i.m.); b.i.d.; for 10 days
Result:Could influence a detectable antibody response to SRBC.
体外研究：
Iodophenpropit is a very potent H3 receptor antagonist and shows only a moderate affinity for the H1 and H2 receptor.Iodophenpropit inhibit 5-hydroxytryptamine (5-HT) responses with an IC50 of 1.57±0.3 μM.
产品资料
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