产品
编 号：F018470
分子式：C14H19N5O4
分子量：321.33
分子式：C14H19N5O4
分子量：321.33
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
50mg
400
In-stock
100mg
680
In-stock
500mg
2040
In-stock
结构图
CAS No: 104227-87-4
产品详情
生物活性：
Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection.
体内研究：
Famciclovir (50-400 mg/kg; p.o. three times per day for total 10 doses) effectively cures necrotic hepatitis mice.Animal Model:Four- to five-week-old Balb/c mice with HSV-1 infection
Dosage:50, 100, 200 and 400 mg/kg
Administration:Oral gavage; 50-400 mg/kg per day divided into three doses given every 8 h; for total 10 doses
Result:Significantly reduced the incidence of hepatitis with a dose of 50 mg/kg per day, and could not isolated infectious virus from the doses of 50 and 100 mg/kg treatment group.
体外研究：
Famciclovir metabolizes into BRL 42359 by deacetylation and then oxidizes to penciclovir.
Famciclovir (BRL 42810) is an orally active nucleoside analogue. Famciclovir is an antiviral agent with potent activities against HBV, HSV and VZV. Famciclovir can be used for the research of herpesvirus infection.
体内研究：
Famciclovir (50-400 mg/kg; p.o. three times per day for total 10 doses) effectively cures necrotic hepatitis mice.Animal Model:Four- to five-week-old Balb/c mice with HSV-1 infection
Dosage:50, 100, 200 and 400 mg/kg
Administration:Oral gavage; 50-400 mg/kg per day divided into three doses given every 8 h; for total 10 doses
Result:Significantly reduced the incidence of hepatitis with a dose of 50 mg/kg per day, and could not isolated infectious virus from the doses of 50 and 100 mg/kg treatment group.
体外研究：
Famciclovir metabolizes into BRL 42359 by deacetylation and then oxidizes to penciclovir.
产品资料
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