产品
编 号：F165992
分子式：C16H20N6O3
分子量：344.37
分子式：C16H20N6O3
分子量：344.37
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 1446418-48-9
产品详情
生物活性：
Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems.
体内研究：
Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice.Animal Model:6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue
Dosage:10 and 20 mg/kg
Administration:Oral gavage; 10-20 mg/kg once
Result:Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis.
Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems.
体内研究：
Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice.Animal Model:6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue
Dosage:10 and 20 mg/kg
Administration:Oral gavage; 10-20 mg/kg once
Result:Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis.
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