产品
编 号：F165113
分子式：C29H31NO4
分子量：457.56
分子式：C29H31NO4
分子量：457.56
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 1443752-76-8
产品详情
生物活性：
OP-1074 is a pure antiestrogen and a selective ER degrader (PA-SERD), shows specific antiestrogenic activity for ERα and ERβ, inhibits 17β-estradiol (E2)-stimulated transcriptional activity with IC50 of 1.6 and 3.2?nM, respectively.
体外研究：
OP-1074 (0-100?nM; 24 hours) inhibits ?MCF-7 cells? and CAMA-1 cells proliferation?with IC50 values of 6.3 and 9.2 nM, respectively.OP-1074 (100?nM; 24 hours) destabilizatizes ERα protein expression in MCF-7 and CAMA-1 cells.
OP-1074 is a pure antiestrogen and a selective ER degrader (PA-SERD), shows specific antiestrogenic activity for ERα and ERβ, inhibits 17β-estradiol (E2)-stimulated transcriptional activity with IC50 of 1.6 and 3.2?nM, respectively.
体外研究：
OP-1074 (0-100?nM; 24 hours) inhibits ?MCF-7 cells? and CAMA-1 cells proliferation?with IC50 values of 6.3 and 9.2 nM, respectively.OP-1074 (100?nM; 24 hours) destabilizatizes ERα protein expression in MCF-7 and CAMA-1 cells.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备