产品
编 号：F164513
分子式：C18H17Cl2N5
分子量：374.27
分子式：C18H17Cl2N5
分子量：374.27
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 1443290-89-8
产品详情
生物活性：
ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels. ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) with EC50s of 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively.
体外研究：
ML67-33 激活 K2P 通道和突变体，对 K2P2.1 (TREK-1) W275S, K2P2.1 (TREK-1)-3G, K2P10.1 (TREK-2), K2P4.1 (TRAAK) 的 EC50 分别为 21.8±1.3 μM, 49.4±1.1 μM, 30.2±1.4 μM, 和 27.3±1.2 μM。
ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels. ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) with EC50s of 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively.
体外研究：
ML67-33 激活 K2P 通道和突变体，对 K2P2.1 (TREK-1) W275S, K2P2.1 (TREK-1)-3G, K2P10.1 (TREK-2), K2P4.1 (TRAAK) 的 EC50 分别为 21.8±1.3 μM, 49.4±1.1 μM, 30.2±1.4 μM, 和 27.3±1.2 μM。
产品资料
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