产品
编 号:F164431
分子式:C21H20FNO3
分子量:353.39
产品类型
结构图
CAS No: 1443118-44-2
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产品详情
生物活性:
ML337 is a selective and brain-penetrant negative allosteric modulator of mGlu3, with an IC50 of 593 nM. ML337 possesses a favorable dystrophia myotonica protein kinase (DMPK) and ancillary pharmacology profile. ML337 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体外研究:
ML337 has no activity at mGlu1, 2, 4, 5, 6, 7 and 8 at concentrations up to 30 μM.