产品
编 号:F162270
分子式:C22H26N2O2S
分子量:382.52
产品类型
结构图
CAS No: 143322-58-1
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产品详情
生物活性:
Eletriptan (UK-116044) is a highly selective and orally active serotonin 5-HT1B and 5-HT1D receptor agonist, with pKi values of 8.0 and 8.9, respectively. Eletriptan has inhibitory effects on markers of neurogenic inflammation in rats. Eletriptan can be used for researching migraine.
体内研究:
Eletriptan (10, 30, 100, 300 and 1000 μg/kg; i.v.) reduces total carotid blood flow in anaesthetised pigs by selectively reducing carotid arteriovenous anastomotic blood flow and increasing nutrient blood flow within the carotid vascular bed.