产品
编 号：F161466
分子式：C31H29N5O3S2
分子量：583.72
分子式：C31H29N5O3S2
分子量：583.72
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CAS No: 1431866-33-9
产品详情
生物活性：
WEHI-539 is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM.
体外研究：
WEHI-539 is a selective inhibitor of Bcl-XL. WEHI-539 augments Carboplatin induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells.
WEHI-539 is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM.
体外研究：
WEHI-539 is a selective inhibitor of Bcl-XL. WEHI-539 augments Carboplatin induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells.
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