产品
编 号:F017520
分子式:C25H34O6
分子量:430.53
产品类型
结构图
CAS No: 1040085-99-1
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产品详情
生物活性:
Budesonide impurity C is an impurity of Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist.
体外研究:
Budesonide is selective for human glucocorticoid receptor (hGR; EC50=45.7 pM) over mineralocorticoid receptors (EC50=7,620 pM) in CV-1 cells. Budesonide (30?min prior to LPS) suppresses the activation of the NLRP3 inflammasome by LPS (100?ng/mL) plus ATP (5?mM) in macrophages (RAW 264.7 cells).