产品
编 号：F160571
分子式：C21H29N5O2
分子量：383.49
分子式：C21H29N5O2
分子量：383.49
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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结构图
CAS No: 1428862-32-1
产品详情
生物活性：
Usmarapride (SUVN-D4010) free base is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM). Usmarapride (SUVN-D4010) free base can be used for the research of cognitive deficits associated with Alzheimer's disease.
体内研究：
Usmarapride (SUVN-D4010) (1-3 mg/kg; p.o.; Male Wistar rats 10-12 weeks old) free base attenuates the long-term memory deficits in object recognition test (ORT).Usmarapride (1, 3, and 10 mg/kg; p.o.) free base significantly reverses the scopolamine-induced amnesia.Usmarapride free base shows a statistically significant effect at 3.0 mg/kg on both exploration time and recognition index.Usmarapride (SUVN-D4010) free base shows good oral exposures, good bioavailability, and good brain exposures in rats.
Usmarapride (SUVN-D4010) free base is a potent, selective, orally active and brain penetrant 5-HT4 receptor partial agonist (EC50=44 nM). Usmarapride (SUVN-D4010) free base can be used for the research of cognitive deficits associated with Alzheimer's disease.
体内研究：
Usmarapride (SUVN-D4010) (1-3 mg/kg; p.o.; Male Wistar rats 10-12 weeks old) free base attenuates the long-term memory deficits in object recognition test (ORT).Usmarapride (1, 3, and 10 mg/kg; p.o.) free base significantly reverses the scopolamine-induced amnesia.Usmarapride free base shows a statistically significant effect at 3.0 mg/kg on both exploration time and recognition index.Usmarapride (SUVN-D4010) free base shows good oral exposures, good bioavailability, and good brain exposures in rats.
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