产品
编 号：F158865
分子式：C13H17N3O2
分子量：247.29
分子式：C13H17N3O2
分子量：247.29
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 14255-87-9
产品详情
生物活性：
Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530?nM, and exhibits a broad-spectrum anthelmintic activity.
体外研究：
Parbendazole is a tubulin destabilizer, with an EC50 of 530?nM, and can induce DNA damage. Parbendazole (2-10 μM) inhibits the assembly of microtubules dose-dependently, with an IC50 of 3 μM. Parbendazole (2-20 μM)-treated cells show an complete absence of microtubules in Vero cells. Parbendazole (up to 10 μM) inhibits the growth of CLd-AXE myxamoebae. Parbendazole (2-5 μM) potently inhibits tubulin purified from the wild-type myxamoebae.
Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530?nM, and exhibits a broad-spectrum anthelmintic activity.
体外研究：
Parbendazole is a tubulin destabilizer, with an EC50 of 530?nM, and can induce DNA damage. Parbendazole (2-10 μM) inhibits the assembly of microtubules dose-dependently, with an IC50 of 3 μM. Parbendazole (2-20 μM)-treated cells show an complete absence of microtubules in Vero cells. Parbendazole (up to 10 μM) inhibits the growth of CLd-AXE myxamoebae. Parbendazole (2-5 μM) potently inhibits tubulin purified from the wild-type myxamoebae.
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