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编 号：F016949
分子式：C23H27N5O8S2
分子量：565.62
分子式：C23H27N5O8S2
分子量：565.62
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CAS No: 103926-82-5
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生物活性：
Sepimostat dimethanesulfonate (FUT-187) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki value of 27.7?μM.
体内研究：
Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect.Animal Model:Male Sprague Dawley rats weighing 150-300?g.
Dosage:Intravitreal injection.
Administration:1 to 100 nmol/eye.
Result:Exhibited neuroprotective effects significantly.
Sepimostat dimethanesulfonate (FUT-187) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki value of 27.7?μM.
体内研究：
Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect.Animal Model:Male Sprague Dawley rats weighing 150-300?g.
Dosage:Intravitreal injection.
Administration:1 to 100 nmol/eye.
Result:Exhibited neuroprotective effects significantly.
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