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编 号:F016948
分子式:C21H19N5O2
分子量:373.41
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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生物活性:
Sepimostat (FUT-187 free base) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat inhibits the Ifenprodil binding with a Ki value of 27.7?μM.

体内研究:
Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect.Animal Model:Male Sprague Dawley rats weighing 150-300?g.
Dosage:Intravitreal injection.
Administration:1 to 100 nmol/eye.
Result:Exhibited neuroprotective effects significantly.
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