产品
编 号:F155859
分子式:C15H13NO2S
分子量:271.33
产品类型
结构图
CAS No: 141992-47-4
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产品详情
生物活性:
NSC 625987 is a specific and high-affinity CDK4 inhibitor with an IC50 of 0.2 μM for CDK4:cyclin D1. NSC 625987 shows >500-fold selectivity for CDK4 over CDK2.
体外研究:
NSC 625987 (10 nM, 50 nM, 100 nM) treatment attenuates the enhanced proliferation of vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) rats by about 35%.