产品
编 号：F155497
分子式：C19H25FN4O5S2
分子量：472.55
分子式：C19H25FN4O5S2
分子量：472.55
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 1418112-77-2
产品详情
生物活性：
Vimnerixin (AZD4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 (CXCR2). Vimnerixin has the potential for the research of inflammatory disease.
体内研究：
Assessment of Pharmacokinetics (PK) profile of Vimnerixin in rat and dog.In Vivo PKRatDog
Predicted hepatic metabolic CL (ml/min per kilogram)1.70.80
Observed CL (ml/min per kilogram)2.40.50
CLrenal (mL/min per kilogram)biliary (mL/min per kilogram)intc1.40.6
VSS (l/kg)0.190.15
T1/2 (h) (PO)1.33.7
(2.7)(8.4)
F (%)4582
Vimnerixin (AZD4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 (CXCR2). Vimnerixin has the potential for the research of inflammatory disease.
体内研究：
Assessment of Pharmacokinetics (PK) profile of Vimnerixin in rat and dog.In Vivo PKRatDog
Predicted hepatic metabolic CL (ml/min per kilogram)1.70.80
Observed CL (ml/min per kilogram)2.40.50
CLrenal (mL/min per kilogram)biliary (mL/min per kilogram)intc1.40.6
VSS (l/kg)0.190.15
T1/2 (h) (PO)1.33.7
(2.7)(8.4)
F (%)4582
产品资料
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