产品
编 号:F155219
分子式:C26H31N3O3
分子量:433.54
产品类型
结构图
CAS No: 1417700-13-0
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产品详情
生物活性:
ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. Antiviral activity.
体外研究:
ML188 (0-30 μM; 48 hours) effectively inhibit SARS-CoV replication in cell culture.Probe ML188 is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action. ML188 yields an antiviral EC50 value ranging from 12.9 to 13.4 μM in mock-infected and SARS-CoV infected cells.