产品
编 号：F154799
分子式：C24H21ClF2N4O5
分子量：518.9
分子式：C24H21ClF2N4O5
分子量：518.9
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 1416663-77-8
产品详情
生物活性：
RO-5963 is a dual p53-MDM2 and p53-MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively.
体外研究：
RO-5963 (10-20 μM; 48 hours) shows much higher apoptotic activity than Nutlin in both MCF7 and ZR75-30 cell lines.RO-5963 (10 μM, 24 hours) effectively activats p53 and elevates p21 and MDM2 levels.
RO-5963 is a dual p53-MDM2 and p53-MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively.
体外研究：
RO-5963 (10-20 μM; 48 hours) shows much higher apoptotic activity than Nutlin in both MCF7 and ZR75-30 cell lines.RO-5963 (10 μM, 24 hours) effectively activats p53 and elevates p21 and MDM2 levels.
产品资料
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