产品
编 号:F153340
分子式:C34H56N10O9
分子量:748.87
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1mg
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5mg
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10mg
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25mg
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生物活性:
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4.

体内研究:
TRAP (1 mg/kg; i.v.) produces a biphasic response in blood pressure in inactin-anesthetized rats.

体外研究:
TRAP-6 (0.01-10 μM) triggers calcium mobilization in Xenopus oocytes heterologously expressing PAR1.?TRAP-6 (0.01-10 μM; 30 min) activates human platelets.?TRAP-6 (100 μM) does not cause the platelets of rabbits or rats to change shape, aggregate, release granule contents, or form thromboxane.
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