产品
编 号：F152308
分子式：C66H103N17O16S
分子量：1422.69
分子式：C66H103N17O16S
分子量：1422.69
产品类型
规格
价格
是否有货
100mg
400
In-stock
结构图
CAS No: 1405-87-4
产品详情
生物活性：
Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor.
体内研究：
Bacitracin (0-100 mg/kg，肌肉注射，每日一次，连续 12 天) 在 HCC 模型中显示出抗肿瘤功效。Animal Model:HCC model (MH134 cells implanted)
Dosage:0, 10, 50, and 100 mg/kg
Administration:Intramuscular injection (i.m), daily for 12 consecutive days.
Result:Decreased tumor volumes. Decreased the percentage of PDI-stained vascular densities.
体外研究：
Bacitracin (64 μg/mL，24 h) 与粘菌素一起显示出对 S. aureus BA01611 的抗菌活性.Bacitracin (64 μg/mL，1或2 h) 破坏细胞表面，使其形成葡萄状细胞团，使得细胞边界模糊不清。
Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor.
体内研究：
Bacitracin (0-100 mg/kg，肌肉注射，每日一次，连续 12 天) 在 HCC 模型中显示出抗肿瘤功效。Animal Model:HCC model (MH134 cells implanted)
Dosage:0, 10, 50, and 100 mg/kg
Administration:Intramuscular injection (i.m), daily for 12 consecutive days.
Result:Decreased tumor volumes. Decreased the percentage of PDI-stained vascular densities.
体外研究：
Bacitracin (64 μg/mL，24 h) 与粘菌素一起显示出对 S. aureus BA01611 的抗菌活性.Bacitracin (64 μg/mL，1或2 h) 破坏细胞表面，使其形成葡萄状细胞团，使得细胞边界模糊不清。
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