产品
编 号：F152267
产品类型
规格
价格
是否有货
500mg
询价
询价
1g
询价
询价
5g
询价
询价
结构图
CAS No: 1405-20-5
产品详情
生物活性：
Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo.
体内研究：
Polymyxin B Sulfate (0.5-120 mg/kg; s.c.) shows antibacterial activities in thigh or lung infection mouse model.Polymyxin B Sulfate (2 mg/kg, s.c.) shows potent in mouse bactericidal effect against E. coli strain IH3080.Animal Model:Eight-week-old, 24-30 g, female Swiss mice
Dosage:0.5-120 mg/kg for thigh infection model; 5-120 mg/kg for lung infection mode
Administration:S.c.
Result:Showed antibacterial activities for three K. pneumoniae strains.
Animal Model:7-9 weeks, female NMRI mice (E. coli IH3080)
Dosage:2 mg/kg
Administration:S.c.
Result:Decreased the bacterial count in a dose dependent manner.
体外研究：
Polymyxin B Sulfate shows antibacterial activities with MICs of 0.5 mg/l for E. coli strain IH3080.
Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo.
体内研究：
Polymyxin B Sulfate (0.5-120 mg/kg; s.c.) shows antibacterial activities in thigh or lung infection mouse model.Polymyxin B Sulfate (2 mg/kg, s.c.) shows potent in mouse bactericidal effect against E. coli strain IH3080.Animal Model:Eight-week-old, 24-30 g, female Swiss mice
Dosage:0.5-120 mg/kg for thigh infection model; 5-120 mg/kg for lung infection mode
Administration:S.c.
Result:Showed antibacterial activities for three K. pneumoniae strains.
Animal Model:7-9 weeks, female NMRI mice (E. coli IH3080)
Dosage:2 mg/kg
Administration:S.c.
Result:Decreased the bacterial count in a dose dependent manner.
体外研究：
Polymyxin B Sulfate shows antibacterial activities with MICs of 0.5 mg/l for E. coli strain IH3080.
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