产品
编 号:F152258
分子式:C23H52N6O25S3
分子量:908.88
产品类型
结构图
CAS No: 1405-10-3
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产品详情
生物活性:
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis.
体外研究:
Neomycin 对除铜绿假单胞菌和厌氧菌外的大多数革兰氏阴性菌有效。它对革兰氏阳性微生物的活性或多或少仅限于葡萄球菌,但长期使用后细菌耐药性随之产生。