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编 号:F152221
分子式:C4H6O4.xNa
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生物活性:
Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten?eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research.

体内研究:
Succinic acid sodium (3.0 or 6.0 mg/kg, PO) increased the percentage of entries into open arms and of time spent on open arms. succinic acid (3.0, 6.0, and 12.0 mg/kg, IP) caused significant increases in food intake during 5 min when compared with the vehicle. Succinic acid sodium (100 mM) infused into rat colons significantly inhibits colonic cell proliferation and reduced crypt size.
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