产品
编 号：F152122
分子式：C22H19N3O2S
分子量：389.47
分子式：C22H19N3O2S
分子量：389.47
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 1404437-62-2
产品详情
生物活性：
ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML281 showed a 550-fold selectivity over AurB and greater than 700-fold selectivity over PKA.target: STK33IC50: 14 nM ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compared to other STK33 inhibitors. Even at the highest concentration tested (10 μM), ML281 had no effect on the viability of KRAS-dependent cancer cells.
体外研究：
ML281 (10 μM；72 小时) 抑制 NCI-H446 细胞的细胞活力。
ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML281 showed a 550-fold selectivity over AurB and greater than 700-fold selectivity over PKA.target: STK33IC50: 14 nM ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compared to other STK33 inhibitors. Even at the highest concentration tested (10 μM), ML281 had no effect on the viability of KRAS-dependent cancer cells.
体外研究：
ML281 (10 μM；72 小时) 抑制 NCI-H446 细胞的细胞活力。
产品资料
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