产品
编 号：F151959
分子式：C12H18FNO3S
分子量：275.34
分子式：C12H18FNO3S
分子量：275.34
产品类型
规格
价格
是否有货
结构图
CAS No: 1403894-72-3
产品详情
生物活性：
Mesdopetam (IRL790) is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam is used for the research of motor and psychiatric complications in Parkinson disease.
体内研究：
Mesdopetam (IRL790) (3.7, 11, 33, or 100 μmol/kg) dose-dependently inhibits the behavioral activation following pretreatment with D-amphetamine or MK-80.Animal Model:Male Sprague-Dawley rats
Dosage:3.7, 11, 33, or 100 μmol/kg (synthesized in-house as HCl salt, was dissolved in physiologic saline (0.9% w/v NaCl)
Administration:s.c. was administered subcutaneously 4 min before the start of recording
Result:Dose-dependently inhibited the behavioral activation following pretreatment with D-amphetamine or MK-801.
Mesdopetam (IRL790) is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam is used for the research of motor and psychiatric complications in Parkinson disease.
体内研究：
Mesdopetam (IRL790) (3.7, 11, 33, or 100 μmol/kg) dose-dependently inhibits the behavioral activation following pretreatment with D-amphetamine or MK-80.Animal Model:Male Sprague-Dawley rats
Dosage:3.7, 11, 33, or 100 μmol/kg (synthesized in-house as HCl salt, was dissolved in physiologic saline (0.9% w/v NaCl)
Administration:s.c. was administered subcutaneously 4 min before the start of recording
Result:Dose-dependently inhibited the behavioral activation following pretreatment with D-amphetamine or MK-801.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备