产品
编 号：F151321
分子式：C46H77NO17
分子量：916.1
分子式：C46H77NO17
分子量：916.1
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
226
In-stock
10mg
316
In-stock
50mg
400
In-stock
100mg
504
In-stock
结构图
CAS No: 1401-69-0
产品详情
生物活性：
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle.
体内研究：
Tylosin (10-500 mg/kg; s.c.) generally suppresses the elevated TNF-α and IL-1β levels and increases the IL-10 levels in the Lipopolysaccharide (LPS) -treated animals.Animal Model:Balb/C mice (2-3 months old, 20-25 g)
Dosage:10 mg/kg, 100 mg/kg, 500 mg/kg
Administration:Subcutaneous injection
Result:Reduced the elevated TNF-α and IL-1β in LPS (250 μg)-treated mice but increased their IL-10 levels.
体外研究：
Tylosin exerts antibacterial effects by binding to 23S rRNA of the bacterial ribosomal 50S subunit .Tylosin also prevents growth of Gram-negative strains, with MICs of 64 μg/mL, 32 μg/mL, 512 μg/mL and 1 μg/mL for M. haemolytica 11935, P. multocida 4407, E. coli ATCC 25922 and E. coli AS19rlmAI, respectively.
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle.
体内研究：
Tylosin (10-500 mg/kg; s.c.) generally suppresses the elevated TNF-α and IL-1β levels and increases the IL-10 levels in the Lipopolysaccharide (LPS) -treated animals.Animal Model:Balb/C mice (2-3 months old, 20-25 g)
Dosage:10 mg/kg, 100 mg/kg, 500 mg/kg
Administration:Subcutaneous injection
Result:Reduced the elevated TNF-α and IL-1β in LPS (250 μg)-treated mice but increased their IL-10 levels.
体外研究：
Tylosin exerts antibacterial effects by binding to 23S rRNA of the bacterial ribosomal 50S subunit .Tylosin also prevents growth of Gram-negative strains, with MICs of 64 μg/mL, 32 μg/mL, 512 μg/mL and 1 μg/mL for M. haemolytica 11935, P. multocida 4407, E. coli ATCC 25922 and E. coli AS19rlmAI, respectively.
产品资料
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