产品
编 号：F151178
分子式：C27H37Cl2N3O2
分子量：506.51
分子式：C27H37Cl2N3O2
分子量：506.51
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 1401463-54-4
产品详情
生物活性：
BAN ORL 24 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) antagonist. BAN ORL 24 has antagonistic effect for nociceptin (NOP) receptor with KI value of 0.24 nM in CHO cell. BAN ORL 24 can be used for the research of cancer and analgesic.
体内研究：
BAN ORL 24 (10 mg/kg; i.v.) attenuates the duration of BPRIM97 thermal antinociception.Animal Model:C57BL/6 mice
Dosage:10 mg/kg
Administration:10 mg/kg; i.v.
Result:Caused inhibition of BPRIM97-induced antinociception at 90-min postinjection.Did not attenuate BPR1M97-induced antinociception in the tail-clip test after 30 min.
体外研究：
BAN ORL 24 has antagonist for NOR and MOR (opioid receptor subtype) with IC50 values of 50 μM and 0.224 μM, respectively.
BAN ORL 24 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) antagonist. BAN ORL 24 has antagonistic effect for nociceptin (NOP) receptor with KI value of 0.24 nM in CHO cell. BAN ORL 24 can be used for the research of cancer and analgesic.
体内研究：
BAN ORL 24 (10 mg/kg; i.v.) attenuates the duration of BPRIM97 thermal antinociception.Animal Model:C57BL/6 mice
Dosage:10 mg/kg
Administration:10 mg/kg; i.v.
Result:Caused inhibition of BPRIM97-induced antinociception at 90-min postinjection.Did not attenuate BPR1M97-induced antinociception in the tail-clip test after 30 min.
体外研究：
BAN ORL 24 has antagonist for NOR and MOR (opioid receptor subtype) with IC50 values of 50 μM and 0.224 μM, respectively.
产品资料
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