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编 号:F151100
分子式:C23H25N3O4S2
分子量:471.59
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
ML277 (CID-53347902) is a potent and selective activator of K(v)7.1 (KCNQ1) potassium channel activator (EC50=270 nM), rescues function of pathophysiologically important mutant channel complexes in human induced pluripotent stem cell-derived cardiomyocytes.

体外研究:
ML277 (1 μM) increases the amplitude of KCNQ1 whole-cell and single-channel currents.
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