产品
编 号:F151100
分子式:C23H25N3O4S2
分子量:471.59
产品类型
结构图
CAS No: 1401242-74-7
联系客服
产品详情
生物活性:
ML277 (CID-53347902) is a potent and selective activator of K(v)7.1 (KCNQ1) potassium channel activator (EC50=270 nM), rescues function of pathophysiologically important mutant channel complexes in human induced pluripotent stem cell-derived cardiomyocytes.
体外研究:
ML277 (1 μM) increases the amplitude of KCNQ1 whole-cell and single-channel currents.