产品
编 号:F148619
分子式:C26H28F3N3O4
分子量:503.51
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
PF-06291874 is a highly potent, non-peptide and orally active glucagon receptor antagonist. PF-06291874 is under the study for type 2 diabetes mellitus (T2DM).

体内研究:
PF-06291874 exposure is approximately dose-proportional with a half-life of ~19.7-22.7 h. PF-06291874 has a fast on and off rate. PF-06291874 is highly bound to human plasma protein, with a mean free fraction of ~0.55%.
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