产品
编 号：F148549
分子式：C22H12ClF3N2O3
分子量：444.79
分子式：C22H12ClF3N2O3
分子量：444.79
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 1392809-08-3
产品详情
生物活性：
MRL-871 (compound 3) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.
体外研究：
MRL-871 (compound 3; 10 μM, 24h) significantly reduces IL-17a mRNA expression 48-fold in EL4 cells.
MRL-871 (compound 3) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.
体外研究：
MRL-871 (compound 3; 10 μM, 24h) significantly reduces IL-17a mRNA expression 48-fold in EL4 cells.
产品资料
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