产品
编 号：F147266
分子式：C17H15Cl2N3O3
分子量：380.23
分子式：C17H15Cl2N3O3
分子量：380.23
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 139051-78-8
产品详情
生物活性：
L-689560 is a potent N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases.
体内研究：
L-689560 (1?mg/kg, ip) significantly reduces the neuroprotective effect of glycine after glycine receptors and the channel activity of NMDA receptors (NMDARs) are suppressed. L-689560 blocks glycine-induced increase of Akt phosphorylation in the MCAO modelAnimal Model:Adult male Sprague-Dawley (SD) rats middle cerebral artery occlusion (MCAO) model
Dosage:1?mg/kg
Administration:IP
Result:Significantly reduced the neuroprotective effect of glycine after glycine receptors.
体外研究：
L-689560 is a 2-carboxytetrahydroquinoline antagonist.
L-689560 is a potent N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases.
体内研究：
L-689560 (1?mg/kg, ip) significantly reduces the neuroprotective effect of glycine after glycine receptors and the channel activity of NMDA receptors (NMDARs) are suppressed. L-689560 blocks glycine-induced increase of Akt phosphorylation in the MCAO modelAnimal Model:Adult male Sprague-Dawley (SD) rats middle cerebral artery occlusion (MCAO) model
Dosage:1?mg/kg
Administration:IP
Result:Significantly reduced the neuroprotective effect of glycine after glycine receptors.
体外研究：
L-689560 is a 2-carboxytetrahydroquinoline antagonist.
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