产品
编 号：F147239
分子式：C38H66N8O7
分子量：746.98
分子式：C38H66N8O7
分子量：746.98
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CAS No: 139026-66-7
产品详情
生物活性：
JMV 449 is a potent neurotensin receptor agonist. JMV 449 shows an IC50 of 0.15 nM for inhibition of [125I]-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 has highly potent and long-lasting hypothermic and analgesic effects in the mouse.
体内研究：
JMV 449 (120 pmol/mouse; i.c.v) shows analgesic effect.Animal Model:Male Swiss albino mice
Dosage:120 pmol/mouse
Administration:i.c.v.
Result:Showed dose-response relation-ships for the analgesic effect.
JMV 449 is a potent neurotensin receptor agonist. JMV 449 shows an IC50 of 0.15 nM for inhibition of [125I]-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 has highly potent and long-lasting hypothermic and analgesic effects in the mouse.
体内研究：
JMV 449 (120 pmol/mouse; i.c.v) shows analgesic effect.Animal Model:Male Swiss albino mice
Dosage:120 pmol/mouse
Administration:i.c.v.
Result:Showed dose-response relation-ships for the analgesic effect.
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