产品
编 号：F015782
分子式：C18H24ClN3O3
分子量：365.85
分子式：C18H24ClN3O3
分子量：365.85
产品类型
规格
价格
是否有货
50mg
560
In-stock
100mg
792
In-stock
1g
960
In-stock
5g
2280
In-stock
结构图
CAS No: 103639-04-9
产品详情
生物活性：
Ondansetron (GR 38032) hydrochloride dehydrate is an orally active, highly selective and competitive 5-HT3 receptor antagonist (crosses the blood-brain barrier). Ondansetron hydrochloride dehydrate can be used in studies of preventing nausea and vomiting associated with cancer chemotherapy, radiation therapy and surgery.
体内研究：
Ondansetron hydrochloride dehydrate (2 mg/kg; i.p.; single) blocks radiation sickness when combines with Dexamethasone (2 mg/kg) and CP-99,994 (15 mg/kg), in radiation-induced pica model.Animal Model:Male mice of ICR strain (8-week-old; 30-36 g; radiation-induced pica model (kaolin ingestion behavior “pica” may be analogous to nausea and vomiting in mice)).
Dosage:2 mg/kg
Administration:Intraperitoneal injection; single.
Result:Slightly reduced the radiation-induced kaolin consumption by dexamethasone to 48% of the control.Showed good activity of blocking radiation sickness by combining with Dexamethasone (2 mg/kg) and CP-99,994 (15 mg/kg).
Ondansetron (GR 38032) hydrochloride dehydrate is an orally active, highly selective and competitive 5-HT3 receptor antagonist (crosses the blood-brain barrier). Ondansetron hydrochloride dehydrate can be used in studies of preventing nausea and vomiting associated with cancer chemotherapy, radiation therapy and surgery.
体内研究：
Ondansetron hydrochloride dehydrate (2 mg/kg; i.p.; single) blocks radiation sickness when combines with Dexamethasone (2 mg/kg) and CP-99,994 (15 mg/kg), in radiation-induced pica model.Animal Model:Male mice of ICR strain (8-week-old; 30-36 g; radiation-induced pica model (kaolin ingestion behavior “pica” may be analogous to nausea and vomiting in mice)).
Dosage:2 mg/kg
Administration:Intraperitoneal injection; single.
Result:Slightly reduced the radiation-induced kaolin consumption by dexamethasone to 48% of the control.Showed good activity of blocking radiation sickness by combining with Dexamethasone (2 mg/kg) and CP-99,994 (15 mg/kg).
产品资料
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