产品
编 号：F146415
分子式：C61H93N19O15S
分子量：1364.57
分子式：C61H93N19O15S
分子量：1364.57
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 138614-30-9
产品详情
生物活性：
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively.
体内研究：
Icatibant acetate (10-30 μM) 增强血管紧张素 III，但不增强血管紧张素 II (由血管紧张素 AT1 受体介导的收缩) 和 Lys-des-Arg9-缓激肽，以及 des-Arg9-缓激肽 (由缓激肽 B1 受体介导的作用)。Animal Model:Female mice of the CBA/J (H-2k) strain.
Dosage:0.06, 0.3, or 1.5 mg/kg.
Administration:Subcutaneous administration twice daily.
Result:The length of the large intestine was 93.6±6.8 mm with the 1.5 mg/kg dosage and 94.0±4.1 mm with the 0.3 mg/kg dosage , showing a significant preventive effect on shortening.
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively.
体内研究：
Icatibant acetate (10-30 μM) 增强血管紧张素 III，但不增强血管紧张素 II (由血管紧张素 AT1 受体介导的收缩) 和 Lys-des-Arg9-缓激肽，以及 des-Arg9-缓激肽 (由缓激肽 B1 受体介导的作用)。Animal Model:Female mice of the CBA/J (H-2k) strain.
Dosage:0.06, 0.3, or 1.5 mg/kg.
Administration:Subcutaneous administration twice daily.
Result:The length of the large intestine was 93.6±6.8 mm with the 1.5 mg/kg dosage and 94.0±4.1 mm with the 0.3 mg/kg dosage , showing a significant preventive effect on shortening.
产品资料
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