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编 号：F146290
分子式：C45H66N18O7S
分子量：1003.19
分子式：C45H66N18O7S
分子量：1003.19
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CAS No: 138559-60-1
产品详情
生物活性：
Antileukinate, a hexapeptide, is a potent inhibitor of CXC-chemokine receptor (CXCR). Antileukinate inhibits neutrophil chemotaxis and activation. Antileukinate can be used for the research of acute inflammation and injury.
体内研究：
Antileukinate (52.63 mg/kg; s.c.) protectes mice against acute pancreatitis and associated lung injury.Antileukinate (5mg/kg; s.c.) inhibits the interaction between murine eotaxin and murine eosinophil.Animal Model:Swiss mice (20-25g)
Dosage:52.63 mg/kg
Administration:Subcutaneous injection
Result:Reduced pancreatic edema induced by Caerulein (50 μg/kg).
体外研究：
Antileukinate inhibits the binding of human eotaxin to human eosinophils with an IC50 of 8.2 μM.Antileukinate (10-100 μM; 2 hours) significantly suppresses eosinophil chemotaxis to human eotaxin.
Antileukinate, a hexapeptide, is a potent inhibitor of CXC-chemokine receptor (CXCR). Antileukinate inhibits neutrophil chemotaxis and activation. Antileukinate can be used for the research of acute inflammation and injury.
体内研究：
Antileukinate (52.63 mg/kg; s.c.) protectes mice against acute pancreatitis and associated lung injury.Antileukinate (5mg/kg; s.c.) inhibits the interaction between murine eotaxin and murine eosinophil.Animal Model:Swiss mice (20-25g)
Dosage:52.63 mg/kg
Administration:Subcutaneous injection
Result:Reduced pancreatic edema induced by Caerulein (50 μg/kg).
体外研究：
Antileukinate inhibits the binding of human eotaxin to human eosinophils with an IC50 of 8.2 μM.Antileukinate (10-100 μM; 2 hours) significantly suppresses eosinophil chemotaxis to human eotaxin.
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