产品
编 号:F145738
分子式:C17H13F3N4O2
分子量:362.31
产品类型
结构图
CAS No: 1384424-80-9
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生物活性:
A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain.