产品
编 号:F144735
分子式:C31H36N2O
分子量:452.63
产品类型
结构图
CAS No: 138046-43-2
联系客服
产品详情
生物活性:
YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
体外研究:
Foam cells accumulated esterified cholesterol (EC) for 24 h in the presence of acLDL without Cu2+, which is suppressed by KY-455 and YM-750.