产品
编 号:F144719
分子式:C25H26ClN3O
分子量:419.95
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
结构图
联系客服
产品详情
生物活性:
JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 impairs metastatic seeding and colonization of breast cancer cells.

体内研究:
JMS-17-2 (10 mg/kg;腹腔注射;每天两次,持续三周) 导致 SCID 小鼠骨骼和内脏器官的肿瘤显著减少。Animal Model:SCID mice (~25g) with MDA-231 xenograft
Dosage:10 mg/kg
Administration:Aministered i.p.; twice a day for three weeks
Result:Caused a dramatic reduction of tumors in both skeleton and visceral organs.
产品资料