产品
编 号:F143466
分子式:C26H38N8O7
分子量:574.63
产品类型
结构图
CAS No: 137813-35-5
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产品详情
生物活性:
Cyclo(Arg-Gly-Asp-D-Phe-Val) (Cyclo(RGDfV)) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia.
体外研究:
Cyclo(Arg-Gly-Asp-d-Phe-Val) (Cyclo(RGDfV)) (35 nM, 4-24 h) disruptes the adhesion and migration between the tumor cells and the matrix, induces the leukemia cells to leave the protective microenvironment and increases their sensitivity to cell cycle-dependent agents.