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编 号:F143332
分子式:C20H23F3N4O3S
分子量:456.48
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect.

体外研究:
Macozinone (PBTZ169) 在体外、离体和体内均对结核分枝杆菌具有高效作用。
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