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编 号:F142009
分子式:C19H19FN2O2
分子量:326.36
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THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)? brain homogenates. 18F-THK-5117 has?the?potential to act as a tau imaging PET probe.
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