产品
编 号：F141749
分子式：C11H12N2O3S
分子量：252.29
分子式：C11H12N2O3S
分子量：252.29
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CAS No: 137338-43-3
产品详情
生物活性：
LAS-31180 is an inhibitor of phosphodiesterase 3, with positive inotropic and vasodilator properties.
体内研究：
In conscious chronically instrumented beagle dogs, LAS 31180 administered either by intravenous or oral route, shows a dose-dependent, long-lasting positive inotropic effect with minimal effects on heart rate. In hypertensive beagle dogs LAS 31180 elicits a potent and long-lasting fall in blood pressure.
体外研究：
LAS 31180 shows positive inotropic activities in isolated guinea-pig ventricular strips (EC50 of 1.2 mumol/L) and in isolated guinea-pig working hearts.
LAS-31180 is an inhibitor of phosphodiesterase 3, with positive inotropic and vasodilator properties.
体内研究：
In conscious chronically instrumented beagle dogs, LAS 31180 administered either by intravenous or oral route, shows a dose-dependent, long-lasting positive inotropic effect with minimal effects on heart rate. In hypertensive beagle dogs LAS 31180 elicits a potent and long-lasting fall in blood pressure.
体外研究：
LAS 31180 shows positive inotropic activities in isolated guinea-pig ventricular strips (EC50 of 1.2 mumol/L) and in isolated guinea-pig working hearts.
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