产品
编 号：F141730
分子式：C23H28N2O8
分子量：460.48
分子式：C23H28N2O8
分子量：460.48
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
2085
In-stock
1mg
823
In-stock
5mg
2058
In-stock
10mg
3300
In-stock
结构图
CAS No: 1373346-85-0
产品详情
生物活性：
M4284 is a selective and orally active biphenyl mannoside FimH antagonist. M4284 has activities against different UPEC (Urinary tract infections (UTI) caused by uropathogenic E. coli) strains in different host genetic backgrounds and gut microbial community contexts.
体内研究：
M4284 (oral administration; 100 mg/kg; 3 doses) can reduces UTI89 levels in the gut and urinary tracts of mice that are concurrently colonized with UTI89 in the gut and bladder. And treating mice with additonal M4284 doses further reduces the UTI89 population and the number of UPEC is lower in M4284-treated mice after termination of treatment.Animal Model:C3H/HeN mice.
Dosage:100 mg/kg
Administration:Oral administation; a single dose.
Result:Had activities against different UPEC strains in different host genetic backgrounds and gut microbial community contexts.
M4284 is a selective and orally active biphenyl mannoside FimH antagonist. M4284 has activities against different UPEC (Urinary tract infections (UTI) caused by uropathogenic E. coli) strains in different host genetic backgrounds and gut microbial community contexts.
体内研究：
M4284 (oral administration; 100 mg/kg; 3 doses) can reduces UTI89 levels in the gut and urinary tracts of mice that are concurrently colonized with UTI89 in the gut and bladder. And treating mice with additonal M4284 doses further reduces the UTI89 population and the number of UPEC is lower in M4284-treated mice after termination of treatment.Animal Model:C3H/HeN mice.
Dosage:100 mg/kg
Administration:Oral administation; a single dose.
Result:Had activities against different UPEC strains in different host genetic backgrounds and gut microbial community contexts.
产品资料
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