产品
编 号:F141713
分子式:C24H33N3O2
分子量:395.54
产品类型
结构图
CAS No: 137328-52-0
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产品详情
生物活性:
LY215840, a 5-HT7 receptor ligand and a 5-HT2 receptor antagonist, blocks serotonin-induced relaxation in canine coronary artery.
体外研究:
LY215840 (1 μM) markedly potentiated contraction to 5-carboxamidotryptamine, the most potent coronary relaxant agonist and the agonist with the highest 5-HT7 receptor affinity.LY215840 (3 x 10-10 to 10-8 M) blocks 5-HT2 receptors mediating contraction to 5-HT in vitro.