产品
编 号：F139702
分子式：C12H18O2
分子量：194.27
分子式：C12H18O2
分子量：194.27
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
320
In-stock
1g
400
In-stock
结构图
CAS No: 136-77-6
产品详情
生物活性：
Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage.
体内研究：
Hexylresorcinol (10 mg/kg; i.p.; daily; for 16 days) inhibits tumor cell proliferation in mouse tumor xenografts and concomitant application of calcium channel blocker partly reverses the antitumor effect of Hexylresorcinol.Animal Model:Male nude mice (BALB/cAnNCrj-nu/nu), with SCC-9 cells xenograft
Dosage:10 mg/kg
Administration:Intraperitoneal injection, daily, for 16 days
Result:Reduced tumor formation in vivo.
体外研究：
Hexylresorcinol potently inhibits Gram positive bacteria, with MICs of 20-50 mg/L for several Gram positive bacteria. Gram negative bacteria, yeasts and fungi are less sensitive to it.Hexylresorcinol inhibits oxidative DNA damage in human lymphocytes by increasing levels of glutathione and modulation of antioxidant enzymes (GPX, GR and GST).Hexylresorcinol (1-10 μg/mL; 24-72 hours) suppresses squamous carcinoma cell line SCC-9 proliferation.Hexylresorcinol has strong antitumor effects by inhibiting calcium channel oscillation and inducing apoptosis.Hexylresorcinol upregulates TGF-β/SMAD/VEGF signaling in endothelial cells and induces vascular regeneration and remodeling for wound healing.
Hexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage.
体内研究：
Hexylresorcinol (10 mg/kg; i.p.; daily; for 16 days) inhibits tumor cell proliferation in mouse tumor xenografts and concomitant application of calcium channel blocker partly reverses the antitumor effect of Hexylresorcinol.Animal Model:Male nude mice (BALB/cAnNCrj-nu/nu), with SCC-9 cells xenograft
Dosage:10 mg/kg
Administration:Intraperitoneal injection, daily, for 16 days
Result:Reduced tumor formation in vivo.
体外研究：
Hexylresorcinol potently inhibits Gram positive bacteria, with MICs of 20-50 mg/L for several Gram positive bacteria. Gram negative bacteria, yeasts and fungi are less sensitive to it.Hexylresorcinol inhibits oxidative DNA damage in human lymphocytes by increasing levels of glutathione and modulation of antioxidant enzymes (GPX, GR and GST).Hexylresorcinol (1-10 μg/mL; 24-72 hours) suppresses squamous carcinoma cell line SCC-9 proliferation.Hexylresorcinol has strong antitumor effects by inhibiting calcium channel oscillation and inducing apoptosis.Hexylresorcinol upregulates TGF-β/SMAD/VEGF signaling in endothelial cells and induces vascular regeneration and remodeling for wound healing.
产品资料
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