产品
编 号：F137884
分子式：C23H30F3N3O4S2
分子量：533.63
分子式：C23H30F3N3O4S2
分子量：533.63
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 1361217-07-3
产品详情
生物活性：
AMG-1694 is a potent glucokinase–glucokinase regulatory protein (GK-GKRP) disruptors and promotes the dissociation of the GK-GKRP complex with an IC50 of 7 nM, indirectly increasing GK enzymatic activity. AMG-1694 potently reverses the inhibitory effect of GKRP on GK activity and promotes GK translocation. AMG-1694 normalizes blood glucose levels in several rodent models of diabetes and lowes blood glucose restricted to diabetic and not normoglycaemic animals.
体外研究：
AMG-1694 is highly effective in restoring the enzymatic activity of GK with an EC50 of 0.020?μM in the presence of GKRP.
AMG-1694 is a potent glucokinase–glucokinase regulatory protein (GK-GKRP) disruptors and promotes the dissociation of the GK-GKRP complex with an IC50 of 7 nM, indirectly increasing GK enzymatic activity. AMG-1694 potently reverses the inhibitory effect of GKRP on GK activity and promotes GK translocation. AMG-1694 normalizes blood glucose levels in several rodent models of diabetes and lowes blood glucose restricted to diabetic and not normoglycaemic animals.
体外研究：
AMG-1694 is highly effective in restoring the enzymatic activity of GK with an EC50 of 0.020?μM in the presence of GKRP.
产品资料
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