产品
编 号：F137132
分子式：C29H30N2O2
分子量：438.56
分子式：C29H30N2O2
分子量：438.56
产品类型
规格
价格
是否有货
结构图
CAS No: 135911-02-3
产品详情
生物活性：
RP 67580 is a non-peptide antagonist of substance P (SP), competitively inhibits the binding of [3H]SP to neurokinin receptor 1 (NK1 receptor) in rat brain membranes with a Ki value of 4.16 nM. RP 67580 is a specific antagonist of NK1 receptors and can be used in the research of pain and neurogenic inflammation.
体内研究：
RP 67580（0.03-1 mg/kg；静脉注射；单剂量）显著抑制神经源性炎症。Animal Model:Male albino Sprague-Dawley rats
Dosage:0.03, 0.1, 0.3, 1 mg/kg
Administration:i.v.; single dose
Result:Potently and dose-dependently inhibited the strong plasma extravasation caused by electrical stimulation of the saphenous nerve for 15 minutes with an ED50 value of 0.15 mg/kg.
RP 67580 is a non-peptide antagonist of substance P (SP), competitively inhibits the binding of [3H]SP to neurokinin receptor 1 (NK1 receptor) in rat brain membranes with a Ki value of 4.16 nM. RP 67580 is a specific antagonist of NK1 receptors and can be used in the research of pain and neurogenic inflammation.
体内研究：
RP 67580（0.03-1 mg/kg；静脉注射；单剂量）显著抑制神经源性炎症。Animal Model:Male albino Sprague-Dawley rats
Dosage:0.03, 0.1, 0.3, 1 mg/kg
Administration:i.v.; single dose
Result:Potently and dose-dependently inhibited the strong plasma extravasation caused by electrical stimulation of the saphenous nerve for 15 minutes with an ED50 value of 0.15 mg/kg.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备