产品
编 号:F136884
分子式:C33H44FN5O3
分子量:577.73
产品类型
结构图
CAS No: 1357920-84-3
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产品详情
生物活性:
Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7?nM for wild-type recombinant ALK kinase.
体内研究:
TSR-011 exerts sustained potent inhibition of ALK-dependent tumour growth in mouse models.
体外研究:
TSR-011 has antitumour activity in the clinical trials.