产品
编 号：F015166
分子式：C8H18N2O4S
分子量：238.3
分子式：C8H18N2O4S
分子量：238.3
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 1034190-08-3
产品详情
生物活性：
ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated proagent of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease.
体内研究：
ALZ-801 (口服给药；172 mg/kg；单剂量) 在血浆和脑中的平均 AUCt 值分别为 58，758 和 5841 ng/mL.h。ALZ-801：Tramiprosate 在雄性 CD-1 小鼠血浆和脑中的比值分别为 1.8 和 3.1。
ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated proagent of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease.
体内研究：
ALZ-801 (口服给药；172 mg/kg；单剂量) 在血浆和脑中的平均 AUCt 值分别为 58，758 和 5841 ng/mL.h。ALZ-801：Tramiprosate 在雄性 CD-1 小鼠血浆和脑中的比值分别为 1.8 和 3.1。
产品资料
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