产品
编 号:F015156
分子式:C25H21F4N3O3
分子量:487.45
产品类型
结构图
CAS No: 1034148-04-3
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产品详情
生物活性:
AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM). AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma.
体外研究:
The affinity of AZD5423 to the glucocorticoid receptor is high with an IC50 of 0.9 nM in a radioligand human glucocorticoid receptor assay, and selectivity towards other steroid hormone receptors is >900-fold.