产品
编 号:F134648
分子式:C15H13Cl2N3O2
分子量:338.19
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
KH-CB19 is a potent CLK (cdc2-like kinase) inhibitor (CLK1 IC50=19.7 nM; CLK3 IC50=530 nM). KH-CB19 shows antiviral activity and inhibits influenza virus replication (IC50=13.6?μM).

体外研究:
KH-CB19 (10 μM; 1 h) shows CLK inhibition on SR protein phosphorylation in human microvascular endothelial cells.KH-CB19 (50?μM; 6 h) inhibits the disruption by CLK4 in A549?cells.
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